Top 151533-22-1 l-5-methyltetrahydrofolate calcium

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Top 151533-22-1 l-5-methyltetrahydrofolate calcium
Top 151533-22-1 l-5-methyltetrahydrofolate calcium
Top 151533-22-1 l-5-methyltetrahydrofolate calcium
Top 151533-22-1 l-5-methyltetrahydrofolate calcium
Top 151533-22-1 l-5-methyltetrahydrofolate calcium
Top 151533-22-1 l-5-methyltetrahydrofolate calcium
Top 151533-22-1 l-5-methyltetrahydrofolate calcium

Top 151533-22-1 l-5-methyltetrahydrofolate calcium

  • Item No.KL-l-5-methyltetrahydrofolate calcium
    MOQ10 Gram
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Top 151533-22-1 l-5-methyltetrahydrofolate calciumintroduce

·  L-5-methyltetrahydrofolate calcium  (Levomefolate calcium)  

· Product name: L-5-Methyltetrahydrofolate calcium 

· Synonym(s) :

· L-5-Methyltetrahydrofolic acid, calcium salt

· L-Methyltetrahydrofolate, calcium salt

· L-Methylfolate, calcium

· L-5-MTHF-Ca

·  Other name:CALCIUML-5-METHYLTETRAHYDROFOLATE; L-5-MTHF-Ca ; (6S)-N-[4-(2-Amino-

· 1,4,5,6,7,8,-hexahydro-5-methyl-4-oxo-6-pteridinylmethylamino)benzoyl]-L-glutaminsure,

· Calciumsalz (1:1); L-5-Methyltetrahydrofolic acid, calcium salt; L-Methyltetrahydrofolate,

· calcium salt; L-Methylfolate, calcium; L-5-MTHF-Ca; Calcium levomefolate

· CAS#:151533-22-1                       

· Appearance:Off-White to Pale Yellow Solid               

· Assay:98.0Min.                    

· Mol.Formula:C20H23CaN7O6     

· Melting Point: >300°C    

· Mol.Weight:497.5179OEM (2)_.jpgfunction

Function

1. Mainly for folic acid antagonists (such as methotrexate, pyrimethamine, benzyl cefalexin and trimethoprim) antidote, it's usually used for prevention of methotrexate dose or overdose treatment caused severe toxic effects.
2. Folic acid treatment of the following diseases, such as inflammatory diarrhea and protein-energy malnutrition (poor nutrition), pregnancy or infancy megaloblastic anemia caused by poor.
3. as adjuvant therapy for colon cancer, rectal cancer.
4. Combined with 5-FU and treatment of digestive tract tumors or other 5-FU-sensitive tumors. High-dose CF used in conjunction with 5-FU (LF), the basic programme is currently the treatment of colon and rectal cancer.
5. For children with leukemia, lymphoma, and osteosarcoma, such as high dose MTX treatment when rescued. 

 

Application:

Calcium salt of L-5-methyltetrahydrofolic acid which belongs to the group of folate vitamins (Vitamin B9, Folacin). 
It is a coenzymated form of folic acid and a more bioavailable alternative in dietary supplements.

Product Name:

L-5-Methyltetrahydrofolic Acid Calcium

CAS No.:

151533-22-1

Manufacture Date:

2014-10-18

Representative Qty.:

10kg

Batch Number:

20141018

ITEM

SPECIFICATION

RESULT

Physical

Appearance

White to yellowish powder

Complies

Identification

IR-spectrum and HPLC retention time comply 

with that of the reference standard, calcium positive

Complies

Specific Rotation 

(C=1.5%in water,25℃)

 

+38.0~+42.00  

 

  +39.10

Calcium(Anhydrous basis)

7.0%-8.5%

8.1%

Sulfate

≤0.015%

complies

Chloride

≤0.021%

Conforms

Water (K-F)

≤17.0%

12.7%

Chemical

Heavy metals (Pb)

≤10ppm

complies

Arsenic (As2O3)

≤1ppm

complies

D-5-Methylfolate

NMT 1.0%

complies

Assay

Assay (HPLC)

98.0%~103.0%

98.2%

 Microorganism

Total plate count

≤1000cuf/g

complies

Mold & Yeasts

≤100cuf/g

complies

Salmonella

Negative

complies

E. Coil

Negative

complies

Else

Storage condition 

Store in sealed containers at cool & dry place.

protect from light,moisture and pest infestation.

Shelf life

Two years when properly stored.

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